Features of Top Avana
Top Avana is a medication designed to improve symptoms of erectile dysfunction (ED) and premature ejaculation (PE).

It combines two ingredients: Avanafil from Stendra, the world's first ED treatment drug, and Dapoxetine from Priligy, a medication for preventing premature ejaculation, characterized by light green diamond-shaped tablets.
■Comparison with Related Products
Top Avana is a dual-action drug of Stendra, a treatment for erectile dysfunction, and Priligy, a medication for preventing premature ejaculation.

It not only provides the benefits of both drugs simultaneously but is also a generic version made from the two active ingredients.

Top Avana is more affordable than purchasing Stendra and Priligy separately.

※The table can be scrolled horizontally.

Medications for treating erectile dysfunction (ED) and preventing premature ejaculation should be taken once per sexual activity.

If you suffer from complications of erectile dysfunction (ED) or premature ejaculation, we recommend taking Top Avana.

Effects of Top Avana
The main ingredients of Top Avana, Avanafil and Dapoxetine, are expected to treat ED (erectile dysfunction) and premature ejaculation, which are common concerns for men.

PDE-5 enzyme breaks down cyclic guanosine monophosphate (cGMP), which is necessary for erection.

When cGMP is broken down, erection cannot occur, a condition known as ED (erectile dysfunction).

Avanafil inhibits the PDE-5 enzyme, dilates blood vessels around the penis, and relaxes the muscles of the internal penile tissue, known as the corpus cavernosum.

This action dilates blood vessels and relaxes muscles, allowing more blood to flow easily into the internal penile tissue (corpus cavernosum), thereby promoting erection.

It is said that one cause of premature ejaculation is serotonin deficiency. Serotonin leads to excessive adrenaline secretion; when the sympathetic nervous system is under excessive stress or in a state of excitement or tension, ejaculation occurs at unintended times.

Serotonin, a neurotransmitter in the brain, is said to balance emotions like excitement and anxiety by inhibiting the activity of dopamine (which enhances pleasure) and norepinephrine (which responds to tension and stress).

Dapoxetine is expected to increase serotonin concentration in the brain by blocking its reuptake at nerve endings, suppressing over-excitement, and prolonging ejaculation time.

It is known that 25% of men with ED also suffer from premature ejaculation, but since ED and premature ejaculation affect different mechanisms, they can be treated simultaneously.

■If Top Avana Does Not Work

If Top Avana is not effective for you, we recommend its sister product Super Avana.
Both are medications produced by the Indian pharmaceutical company Sunrise Remedies, but they contain different amounts of ingredients.

Top Avana	Avanafil: 50 mg Dapoxetine: 30 mg
Super Avana	Avanafil: 100/200 mg Dapoxetine: 60 mg

Super Avana contains twice the amount of Dapoxetine, so you can expect stronger effects.
If Top Avana does not work for you, try Super Avana.

⇒Click here for details on Super Avana

Duration of Top Avana's Effects
The effects are said to last 3 to 6 hours, but taking the medication does not force an erection; erection occurs only when sexually stimulated or aroused.

Ingredient of Top Avana
You can purchase Avanafil 50 mg / Dapoxetine 30 mg from our personal import handling website.

Other Information
Top Avana is the preferred medication for treating erectile dysfunction (ED) and premature ejaculation.

※It is reported that about 25% of patients with erectile dysfunction also suffer from premature ejaculation.

Popular Products Related to Avana
Other Erectile Dysfunction (ED) Treatment List
・ED Medications

Medications for Preventing Premature Ejaculation
・Poxet

Timing of Administration
The correct way to take Top Avana is on an empty stomach, 30 minutes to 1 hour before sexual activity.

After the first dose, wait at least 24 hours before taking another dose.

Recommended Dosage
Each Top Avana tablet contains 50mg of Avanafil and 30mg of Dapoxetine as active ingredients.

Some users may take 2-3 times the prescribed dose for stronger effects, but this does not enhance efficacy.

The maximum single-dose amount of Avanafil per sexual activity is 200mg.

The maximum single-dose amount of Dapoxetine per sexual activity is 60mg.

Wait at least 24 hours before taking Top Avana again.

Recommended Starting Dosage
First-time users of medications containing Avanafil should start with 50mg.

First-time users of medications containing Dapoxetine should start with 30mg.

Food Interactions
Top Avana has minimal impact from food, but the manufacturer recommends that meals under 700kcal with fat content not exceeding 30% do not affect absorption.

Avanafil's water-soluble nature provides rapid action.

Take it 30 minutes before meals to promote ingredient absorption and minimize food interference.

If taken after a meal, wait at least 2 hours.

Insufficient digestion of food may affect drug absorption.

High-fat meals like grilled or fried foods require longer digestion; it is recommended to take on an empty stomach.

Normal eating can resume after the drug is absorbed.

Alcohol Interactions
Dapoxetine can intensify alcohol side effects; simultaneous consumption is prohibited.

Alcohol intake should occur 1-4 hours after taking the medication.

Both alcohol and Dapoxetine affect serotonin/norepinephrine, potentially causing nausea, palpitations, headache, night sweats, hangover, or even fainting.

Contraindications
・Cardiovascular disease (unsuitable for sexual activity)

・Severe hepatic impairment

・Hypotension or uncontrolled hypertension

・History of stroke or cerebral hemorrhage within the past 6 months

・Severe angina or myocardial infarction

・Severe heart valve disease

・Sick sinus syndrome

・History of orthostatic hypotension or fainting

・Depression or bipolar disorder

・Epilepsy patients

・Under 20 or over 65 years old

※Please take as directed by your doctor.

Main Side Effects
The main side effects include a decrease in blood pressure due to vasodilation, eye congestion, facial flushing, palpitations, nasal congestion, headache, dry mouth, dizziness, and nausea.

These are believed to be caused by vasodilation, and the side effects may diminish when sexual desire enhances blood flow to the penis.

Specific Symptoms
Specific symptoms include visual abnormalities, such as feeling like wearing blue-tinted glasses, or an inability to distinguish between blue and green.

In most cases, this is temporary and causes no problems, but if vision severely deteriorates, there is a risk of developing non-arteritic anterior ischemic optic neuropathy (NAION).

If you experience sudden vision loss or impairment, consult an ophthalmologist or other specialist.

Additionally, if you experience a painful erection lasting more than four hours, you may have priapism.

If your erection persists for more than four hours, seek immediate medical attention.

※ What is Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)?
When the blood supply to the optic nerve stops, optic nerve cells begin to malfunction or die. This condition is called ischemic optic neuropathy.
The causal relationship is unclear, but there is said to be a slight correlation between this disease and people taking erectile dysfunction medications.

※ What is Priapism?
Priapism, also known as persistent erection, refers to a condition where the penis remains erect and cannot return to normal or is difficult to restore to normal.
It is also called penile rigidity.
The main cause is believed to be rupture of the penile corpus cavernosum arterial system.
If your erection does not return to normal after four continuous hours, seek immediate medical attention.

Contraindicated concomitant medications
Drugs that should not be taken simultaneously refer to those that are incompatible with Top Avana and cannot be taken together.

・ Nitrates and nitric oxide donors
(Nitroglycerin, Amyl Nitrite, Isosorbide Dinitrate)
Concomitant use may enhance the antihypertensive effect.

・ Amiodarone Hydrochloride
(Ancarone Tablets)
Concomitant use may enhance the QTc prolongation effect of Amiodarone Hydrochloride.

・ CYP3A4 inhibitors
(Antifungals, antibiotics, anti-HIV drugs, telithromycin, nelfinavir, ketoconazole, itraconazole, ritonavir, saquinavir, nelfinavir, atazanavir, clarithromycin, telithromycin, etc.)
The blood concentration of this drug may increase, and its half-life in the blood may be prolonged.

・ Serotonergic drugs
(SSRIs, SNRIs, tricyclic antidepressants, L-tryptophan, triptans, tramadol, linezolid, lithium, St. John's Wort)

・ MAO inhibitors (antidepressants)
When used concomitantly with dapoxetine, they may cause autonomic instability, such as abnormally high fever, rigidity, mental instability, and delirium.

・ Psychiatric drugs
(Thioridazine)

Contraindications for concomitant use with other drugs
Drugs that require caution when co-administered with Top Avana are those that need careful consideration when taken together with Top Avana.

・ Grapefruit (including juice)
The component furanocoumarin inhibits the action of metabolic enzymes in the body, slowing down the breakdown of the drug.
As a result, drug components may be absorbed by the body in amounts exceeding what is required, potentially leading to stronger effects and side effects.

・ Antihypertensive drugs
Top Avana has blood pressure-lowering effects, and concomitant use with antihypertensive drugs may cause hypotension symptoms, such as temporary dizziness or lightheadedness.

・Store in a cool, dry place away from direct sunlight.

・Keep out of reach of children.

・To prevent accidental ingestion or spoilage, do not transfer from the original container.

・If dividing the remaining medicine from a single-dose package, store it airtight and consume within 2 days.

・Do not consume or use products beyond the expiration date.

Sunrise Remedies