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Vardetron
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| Product Name | Vardetron
|
| Active ingredients | Vardenafil |
| Influence | Improving Erectile Dysfunction |
| side effect | Decreased blood pressure, eye redness, facial flushing, palpitations, nasal congestion, etc. |
| Directions | Take one tablet 20 minutes to 1 hour before sexual activity. |
| Manufacturing element | Naiom Healthcare
|
Product Details
Vardetron is an ED treatment drug with vardenafil as its main component, and it is a generic drug containing the same active ingredient as the original drug Levitra.
This product is suitable for the following individuals:
The active ingredient vardenafil helps achieve strong erectile strength. Vardetron offers excellent rapid onset, with effects noticeable approximately 15–30 minutes after intake.
Compared to sildenafil, the active ingredient in Viagra, vardenafil is less affected by food and does not require careful timing of intake.
As a more economical generic alternative to the original drug Levitra, it is recommended for those seeking significant efficacy while controlling costs.
A clinical trial compared the insertion frequency and erection maintenance ability over 4 weeks between a placebo group, a vardenafil 5mg group, and a vardenafil 10mg group.
※Insertion frequency is evaluated based on actual counts
※Erection maintenance is self-assessed using the International Index of Erectile Function (international standard for ED severity)
The data show that both the vardenafil 5mg and 10mg groups significantly outperformed the placebo group in insertion frequency and erection maintenance.
Overseas clinical trial reports are as follows:
＜North America Phase III Trial＞
＜Europe Phase III Trial＞
Both North American and European trials showed that the vardenafil 5mg and 10mg groups significantly outperformed the placebo group.
The differences between the original drug Levitra and Vardetron are as follows:
Although there are differences in manufacturers and price, Vardetron, as a generic drug, has equivalent active ingredients and efficacy to the original drug.
The Naiom Healthcare series of ED treatment drugs are as follows:
※This table supports horizontal scrolling
There are many types of ED treatment drugs, differing not only in active ingredients but also in duration of action, side effects, and food interactions.
For optimal efficacy, it is recommended to choose an ED treatment drug that suits your needs and physical constitution.
Levitra generic series
・Levitra Generics
Recommended Users
This product is suitable for the following individuals:
- For those who need strong erectile strength
- For those who prioritize rapid onset of action
- For those who wish to control treatment costs
- For those who require ED treatment drugs less affected by food
- For those seeking generic alternatives to Levitra
The active ingredient vardenafil helps achieve strong erectile strength. Vardetron offers excellent rapid onset, with effects noticeable approximately 15–30 minutes after intake.
Compared to sildenafil, the active ingredient in Viagra, vardenafil is less affected by food and does not require careful timing of intake.
As a more economical generic alternative to the original drug Levitra, it is recommended for those seeking significant efficacy while controlling costs.
Clinical Trials (Insertion Frequency and Erection Maintenance)
A clinical trial compared the insertion frequency and erection maintenance ability over 4 weeks between a placebo group, a vardenafil 5mg group, and a vardenafil 10mg group.
| Item | Placebo Group | Vardenafil 5mg Group | Vardenafil 10mg Group |
|---|---|---|---|
| Insertion Frequency (times) | 2.6→3.2 (post-treatment +0.6) | 2.9→4.1 (post-treatment +1.2) | 2.8→4.5 (post-treatment +1.7) |
| Erection Maintenance | 1.5→2.3 (post-treatment +0.8) | 1.6→3.5 (post-treatment +1.9) | 1.5→4.2 (post-treatment +2.7) |
※Erection maintenance is self-assessed using the International Index of Erectile Function (international standard for ED severity)
The data show that both the vardenafil 5mg and 10mg groups significantly outperformed the placebo group in insertion frequency and erection maintenance.
Overseas Trials (Insertion Success Rate and Erection Maintenance Rate)
Overseas clinical trial reports are as follows:
Evaluation Items
●International Index of Erectile Function: Scored based on international standards
●Insertion Success Rate: Proportion of successful insertions
●Erection Maintenance Rate: Proportion of maintaining erection after insertion
●International Index of Erectile Function: Scored based on international standards
●Insertion Success Rate: Proportion of successful insertions
●Erection Maintenance Rate: Proportion of maintaining erection after insertion
＜North America Phase III Trial＞
| Item | Placebo Group | Vardenafil 5mg Group | Vardenafil 10mg Group |
|---|---|---|---|
| International Index of Erectile Function | 13.6→15.0 (post-treatment +1.4) | 12.5→18.4 (post-treatment +5.9) | 13.4→20.6 (post-treatment +7.2) |
| Insertion Success Rate(%) | 46.0→51.7 (post-treatment +5.7) | 42.8→65.5 (post-treatment +22.7) | 45.4→75.5 (post-treatment +30.1) |
| Erection Maintenance Rate(%) | 14.9→32.2 (post-treatment +17.3) | 10.4→50.6 (post-treatment +40.2) | 14.6→64.5 (post-treatment +49.9) |
＜Europe Phase III Trial＞
| Item | Placebo Group | Vardenafil 5mg Group | Vardenafil 10mg Group |
|---|---|---|---|
| International Index of Erectile Function | 13.0→13.2 (post-treatment +0.2) | 13.2→19.8 (post-treatment +6.6) | 13.0→20.9 (post-treatment +7.9) |
| Insertion Success Rate(%) | 41.7→45.3 (post-treatment +3.6) | 47.8→71.7 (post-treatment +23.9) | 43.9→76.4 (post-treatment +32.5) |
| Erection Maintenance Rate(%) | 15.9→24.9 (post-treatment +9.0) | 14.6→54.9 (post-treatment +40.3) | 15.9→61.6 (post-treatment +45.7) |
Both North American and European trials showed that the vardenafil 5mg and 10mg groups significantly outperformed the placebo group.
Comparison with the Original Drug (Levitra)
The differences between the original drug Levitra and Vardetron are as follows:
Although there are differences in manufacturers and price, Vardetron, as a generic drug, has equivalent active ingredients and efficacy to the original drug.
Naiom Series Products
The Naiom Healthcare series of ED treatment drugs are as follows:
| Image | |
|
|
|
|
|
|---|---|---|---|---|---|---|
| Features | Levitra generic | Levitra generic
Priligy generic |
Cialis generic | Cialis generic
Priligy generic |
Viagra generic | Viagra generic
Priligy generic |
| Active Ingredients | Vardenafil | Vardenafil
Dapoxetine |
Tadalafil | Tadalafil
Dapoxetine |
Sildenafil | Sildenafil
Dapoxetine |
| Efficacy | Improves ED
Enhances male function |
Improves ED
Enhances male function Delays ejaculation |
Improves ED
Enhances male function |
Improves ED
Enhances male function Delays ejaculation |
Improves ED
Enhances male function |
Improves ED
Enhances male function Delays ejaculation |
| Suitable For | Those seeking rapid onset | Those needing rapid onset + high-efficiency delay | Those needing long-lasting maintenance | Those needing long-lasting + high-efficiency delay | Those needing strong erection | Those needing strong erection + high-efficiency delay |
| Product |
There are many types of ED treatment drugs, differing not only in active ingredients but also in duration of action, side effects, and food interactions.
For optimal efficacy, it is recommended to choose an ED treatment drug that suits your needs and physical constitution.
Related Products
Levitra generic series
・Levitra Generics
Usage Method
Vardetron Administration Timing
Vardetron should be taken on an empty stomach, one hour before sexual activity, for proper usage.
After the first dose, the next dose should be taken at least 24 hours apart.
Vardetron Recommended Dosage
The maximum single dose is 20mg.
Using a pill cutter, the tablet can be divided into doses of 5mg or 10mg. Taking more than 20mg will not enhance the effect.
Precautions for Taking Vardetron
The following individuals should take Vardetron with caution:
・Individuals with structural penile problems (such as penile fibrosis, curvature, Peyronie's disease, etc.)
・Individuals with diseases at risk of priapism (such as multiple myeloma, sickle cell anemia, leukemia, etc.)
・Individuals currently using PDE5 inhibitors or other ED treatment medications
・Patients with bleeding disorders or peptic ulcers
・Patients with aortic stenosis or diseases causing obstruction of left ventricular outflow (such as idiopathic hypertrophic subaortic stenosis)
・Individuals with moderate hepatic impairment
・Elderly individuals
・Individuals with diseases at risk of priapism (such as multiple myeloma, sickle cell anemia, leukemia, etc.)
・Individuals currently using PDE5 inhibitors or other ED treatment medications
・Patients with bleeding disorders or peptic ulcers
・Patients with aortic stenosis or diseases causing obstruction of left ventricular outflow (such as idiopathic hypertrophic subaortic stenosis)
・Individuals with moderate hepatic impairment
・Elderly individuals
Individuals Prohibited from Taking Vardetron
The following individuals are prohibited from taking Vardetron:
●Individuals with a history of allergy to the active ingredient
●Individuals currently using nitrates or nitric oxide (NO) donor drugs (such as amyl nitrite, nitroglycerin, nicorandil, isosorbide dinitrate, etc.)
●Individuals with cardiovascular or cerebrovascular diseases judged to be at risk during sexual activity
●Patients with congenital QT prolongation syndrome, or those taking specific antiarrhythmic drugs (such as procainamide, quinidine, sotalol, amiodarone, etc.)
●Individuals who have experienced cerebral hemorrhage, cerebral infarction, or myocardial infarction within the past 6 months
●Individuals with severe hepatic impairment
●Individuals undergoing hemodialysis due to renal failure
●Individuals with hypotension or uncontrolled hypertension
●Patients with unstable angina
●Individuals currently using riociguat or CYP3A4 inhibitors (such as atazanavir, ritonavir, ketoconazole, etc.)
●Patients with retinitis pigmentosa
●Individuals currently using nitrates or nitric oxide (NO) donor drugs (such as amyl nitrite, nitroglycerin, nicorandil, isosorbide dinitrate, etc.)
●Individuals with cardiovascular or cerebrovascular diseases judged to be at risk during sexual activity
●Patients with congenital QT prolongation syndrome, or those taking specific antiarrhythmic drugs (such as procainamide, quinidine, sotalol, amiodarone, etc.)
●Individuals who have experienced cerebral hemorrhage, cerebral infarction, or myocardial infarction within the past 6 months
●Individuals with severe hepatic impairment
●Individuals undergoing hemodialysis due to renal failure
●Individuals with hypotension or uncontrolled hypertension
●Patients with unstable angina
●Individuals currently using riociguat or CYP3A4 inhibitors (such as atazanavir, ritonavir, ketoconazole, etc.)
●Patients with retinitis pigmentosa
If you fall under any of the above categories, please consult your doctor before taking Vardetron.
Side Effects
Main Side Effects of Vardetron
The main side effects of Vardenafil are as follows:
◇More than 1%◇
・Hot flashes (10.6%)
・Headache (11.7%)
・Palpitations (rapid heartbeat)
・Dizziness
・Stomach discomfort (dyspepsia)
・Nasal congestion
・Nausea
etc.
◇0.1% to 1%◇
・Increased pulse rate
・Difficulty falling asleep, insomnia
・Lightheadedness
・Hypertension
・Paresthesia
・Severe drowsiness
・Abnormal liver function tests
・Hypoesthesia
etc.
◇Less than 0.1%◇
・Loss of consciousness
・Myocardial ischemia
・Hypotension
・Severe anxiety
・Facial swelling
・Flu-like symptoms
・Allergic reaction
・Ejaculation disorder
・Persistent abnormal erection
etc.
Frequency unknown
・Angina
・Dizziness and fainting due to orthostatic hypotension
・Glaucoma
Drugs Contraindicated for Combined Use
Contraindications for Valdetron Use
The drugs contraindicated for combined use with Valdetron are as follows.
・Drugs for angina and heart treatment (nitrates and NO donors: nitroglycerin, isosorbide dinitrate, etc.)
・Vasodilators (riociguat)
・CYP3A4 inhibitors (atazanavir, ritonavir, lopinavir/ritonavir, fosamprenavir, itraconazole, nirmatrelvir/ritonavir, encorafenib, ketoconazole (excluding topical preparations), darunavir combination products, cobicistat combination products)
・Class IA antiarrhythmics (sotalol, procainamide, quinidine, pirmenol/disopyramide (oral preparations))
・Class III antiarrhythmics (amiodarone (oral preparations), sotalol)
・Vasodilators (riociguat)
・CYP3A4 inhibitors (atazanavir, ritonavir, lopinavir/ritonavir, fosamprenavir, itraconazole, nirmatrelvir/ritonavir, encorafenib, ketoconazole (excluding topical preparations), darunavir combination products, cobicistat combination products)
・Class IA antiarrhythmics (sotalol, procainamide, quinidine, pirmenol/disopyramide (oral preparations))
・Class III antiarrhythmics (amiodarone (oral preparations), sotalol)
Precautions for Combined Use with Valdetron
The following points should be noted for combined use with Valdetron:
・CYP3A4 inhibitors (macrolide antibiotics)
・Bicalutamide
・CYP3A4 inducers (rifampin, etc.)
・Carperitide
・Alpha-blockers (tamsulosin, terazosin, etc.)
・Bicalutamide
・CYP3A4 inducers (rifampin, etc.)
・Carperitide
・Alpha-blockers (tamsulosin, terazosin, etc.)
Storage Instructions
Please note the following storage precautions:
● Store in a place avoiding direct sunlight, low humidity, and cool.
● Store in a place out of reach of children.
● To prevent the risk of accidental ingestion and maintain quality stability, do not change the original container.
● If you need to take divided tablets multiple times, store them as airtight as possible and consume within 2 days.
● Do not consume or use products beyond the expiration date indicated on the packaging.
● Store in a place out of reach of children.
● To prevent the risk of accidental ingestion and maintain quality stability, do not change the original container.
● If you need to take divided tablets multiple times, store them as airtight as possible and consume within 2 days.
● Do not consume or use products beyond the expiration date indicated on the packaging.
Manufacturer
Naiom Healthcare
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